Detailed solution introduction
LumiSTAR Biotechnology is an expert in designs of a range of protein-based indicators for cellular dynamics measurements. Our expertise includes photochemistry, induced pluripotent stem cell (iPSC) technology, optogenetic tools and regenerative medicine. All of these technologies are packaged into a high content all-optical platform for phenotypic screening, drug discovery, and toxicity testing; the other application is for precision/personalized medicine. This high content platform enables customers to do their drug screening tasks in a more efficient and economical way. We offer a variety of functional assays or iPSC cell lines for different disease modelling; customization service is also available.
Applications of Bio-imaging Platforms incorporated with iPSC Technology.
(1) High Content Drug Discovery: Our platforms enable real-time monitoring cellular dynamics for high content screening. Protein-based reporters are non-toxic to the cells compared with traditional chemical dyes. Also, by incorporation with hiPSC, the whole platforms allow fast phenotypic screening for drug discovery/repurposing and toxicity test, effectively shorten the proof of concept cycle to hit the right target.
(2) Precision/Personalized Medicine: LumiSTAR’s live reporters can be incorporated into customized organs on chips (derived from individual’s iPS cells) for direct signal read out. Direct drug testing can be done on your own cells, your own organs chips!